Entropic effects in cell lineage tree packings
نویسندگان
چکیده
منابع مشابه
Cell lineage tree models of neurogenesis.
The production of neurons to form the mammalian cortex, known as embryonic cortical neurogenesis, is a complex developmental process. Insight into the process of cell division during neurogenesis is provided by murine cortical cell lineage trees, recorded through experimental observation. Recurring patterns within cell lineage trees may be indicative of predetermined cell behaviour. The applica...
متن کاملAsymptotically Optimal Tree-Packings in Regular Graphs
Let T be a tree with t vertices. Clearly, an n vertex graph contains at most n/t vertex disjoint trees isomorphic to T . In this paper we show that for every > 0, there exists a D( , t) > 0 such that, if d > D( , t) and G is a simple d-regular graph on n vertices, then G contains at least (1− )n/t vertex disjoint trees isomorphic to T .
متن کاملGenomic Variability within an Organism Exposes Its Cell Lineage Tree
What is the lineage relation among the cells of an organism? The answer is sought by developmental biology, immunology, stem cell research, brain research, and cancer research, yet complete cell lineage trees have been reconstructed only for simple organisms such as Caenorhabditis elegans. We discovered that somatic mutations accumulated during normal development of a higher organism implicitly...
متن کاملEvaluation of Cell Growth Inhibition of Bifidobacterium Bifidum Cell-free Supernatant Extract on 4T1Tumor Cell Lineage
Background: Cancer is amongst the leading reasons of death in all parts of the world. Breast cancer is also responsible for the largest number of deaths among women population. Several studies confirmed that Bifidobacterium bifidum as a probiotic meaningfully inhibited breast cancer development. The present study aimed to investigate the effect of B. bifidum supernatant on the cell growth inhib...
متن کاملP-130: Piwil2 Reprograms Human Fibroblasts to Germ Cell Lineage
Background The piwi family genes are highly conserved during evolution and play a crucial role in stem cell self-renewal, gametogenesis, and RNA interference in diverse organisms ranging from Arabidopsis to humans. Piwil2, also known as Hili, is one of the four human homologues of piwi. Piwil2 was found in germ cells of adult testis, suggesting that this gene functions in spermatogonial stem ce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Physics
سال: 2018
ISSN: 1745-2473,1745-2481
DOI: 10.1038/s41567-018-0202-0